About
PTNG’s mission is to provide scientifically accurate, cutting-edge support and advice in protein engineering to businesses and universities.
The clinical success of a protein therapeutic depends on critical factors:
Manufacturing yield & cost of goods
Thermal stability & shelf-life
Aggregation
Immunogenicity
Protein engineering can de-risk your project and improve the chances of clinical success
Tap into 3 decades of expertise in:
- X-ray crystallography, NMR and CryoEM
- Molecular dynamics simulations
- Protein engineering for stability and function
- Molecular recognition
- Protein-protein interactions
- Drug design
- Biophysics
- Biosensors
We are visual
As structural biologists we understand the importance of visualisation to portray complex scientific concepts. We work with Biovidera to provide aesthetically appealing and scientifically accurate, simple and compelling visualisation.
For example, this image shows the human epidermal growth factor receptor 2 (HER2; white) embedded in the plasma membrane of a human cell, interacting with Pertuzumab, an FDA-approved monoclonal antibody (yellow). Pertuzumab blocks the HER2 signaling cascade by preventing formation of HER2:HER3 complexes, which play a key role in oncogenesis.
